Version 5.4
Mus musculus Protein: Sep15
Summary
InnateDB Protein IDBP-197617.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Sep15
Protein Name selenoprotein
Synonyms 9430015P09Rik;
Species Mus musculus
Ensembl Protein ENSMUSP00000046910
InnateDB Gene IDBG-197615 (Sep15)
Protein Structure
UniProt Annotation
Function May be involved in redox reactions associated with the formation of disulfide bonds. May contribute to the quality control of protein folding in the endoplasmic reticulum (By similarity). {ECO:0000250}.
Subcellular Localization Endoplasmic reticulum lumen {ECO:0000250}. Note=The association with UGGT1/UGCGL1 is essential for its retention in the endoplasmic reticulum. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008430 selenium binding
Biological Process
GO:0051084 'de novo' posttranslational protein folding
Cellular Component
GO:0005788 endoplasmic reticulum lumen
Protein Structure and Domains
PDB ID MGI:1927947
InterPro IPR012336 Thioredoxin-like fold
IPR014912 Sep15/SelM redox
PFAM PF13098
PF13192
PF13462
PF13905
PF08806
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9ERR7
PhosphoSite PhosphoSite-Q9ERR7
TrEMBL
UniProt Splice Variant
Entrez Gene 93684
UniGene
RefSeq NP_444332
MGI ID
MGI Symbol Sep15
OMIM
CCDS CCDS17884
HPRD
IMGT
EMBL AF288740 AK020419 AK159085 AK159353 BC019792
GenPept AAG31765 AAH19792 BAC55255 BAE34803 BAE35012

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca