Version 5.4
Mus musculus Protein: Slc30a6
Summary
InnateDB Protein IDBP-197854.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Slc30a6
Protein Name solute carrier family 30 (zinc transporter), member 6
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000024870
InnateDB Gene IDBG-197852 (Slc30a6)
Protein Structure
UniProt Annotation
Function Zinc-efflux transporter which allocates the cytoplasmic zinc to the trans-Golgi network (TGN) as well as the vesicular compartment. {ECO:0000269PubMed:11997387}.
Subcellular Localization Golgi apparatus, trans-Golgi network membrane {ECO:0000269PubMed:11997387}; Multi-pass membrane protein {ECO:0000269PubMed:11997387}. Note=Found in vesicles.
Disease Associations
Tissue Specificity Expressed in brain and liver, and to a lower extent also in lung. Highly expressed in brain (at protein level). {ECO:0000269PubMed:11997387}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005385 zinc ion transmembrane transporter activity
GO:0008324 cation transmembrane transporter activity
Biological Process
GO:0006812 cation transport
GO:0006829 zinc ion transport
GO:0006895 Golgi to endosome transport
GO:0055085 transmembrane transport
GO:0071577 zinc ion transmembrane transport
Cellular Component
GO:0005739 mitochondrion
GO:0005794 Golgi apparatus
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:2386741
InterPro IPR002524 Cation efflux protein
PFAM PF01545
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8BJM5
PhosphoSite PhosphoSite-Q8BJM5
TrEMBL
UniProt Splice Variant
Entrez Gene 210148
UniGene Mm.412961
RefSeq NP_659047
MGI ID
MGI Symbol Slc30a6
OMIM
CCDS CCDS37691
HPRD
IMGT
EMBL AF233346 AF395840 AK082907 AK150342 AK151120 BC005753 BC066162 BC068169
GenPept AAH05753 AAH66162 AAH68169 AAL83717 AAM27917 BAC38680 BAE29482 BAE30129

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca