Version 5.4
Mus musculus Protein: Zfp46
Summary
InnateDB Protein IDBP-197908.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Zfp46
Protein Name zinc finger protein 46
Synonyms AI426962; Mlz-4; Zfp-46; Znf436;
Species Mus musculus
Ensembl Protein ENSMUSP00000070216
InnateDB Gene IDBG-197906 (Zfp46)
Protein Structure
UniProt Annotation
Function May be involved in transcriptional regulation.
Subcellular Localization Nucleus {ECO:0000305}.
Disease Associations
Tissue Specificity Lens, liver, heart, kidney, spleen and brain. {ECO:0000269PubMed:8444344}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
GO:0046872 metal ion binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID MGI:99192
InterPro IPR001909 Krueppel-associated box
IPR007087 Zinc finger, C2H2
IPR015880 Zinc finger, C2H2-like
PFAM PF01352
PF00096
PRINTS
PIRSF
SMART SM00349
SM00355
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8BPP0
PhosphoSite PhosphoSite-
TrEMBL Q923E2
UniProt Splice Variant
Entrez Gene 22704
UniGene Mm.1504
RefSeq NP_033583
MGI ID
MGI Symbol Zfp46
OMIM
CCDS CCDS18804
HPRD
IMGT
EMBL AK051031 AK053652 AK136405 AK148255 AK173240 AL935264 BC006587 BC092398 CH466552 M98502
GenPept AAA39949 AAH06587 AAH92398 BAC34503 BAC35464 BAD32518 BAE22966 BAE28441 EDL29943

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca