InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: 1190005F20Rik

Summary

InnateDB Protein

IDBP-198080.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

1190005F20Rik

Protein Name

RIKEN cDNA 1190005F20 gene

Synonyms

1190005F20Rik; AW226554; C1orf25; Trm1-like; Trm1l;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000068309

InnateDB Gene

IDBG-198078 (1190005F20Rik)

Protein Structure

UniProt Annotation

Function

May play a role in motor coordination and exploratory behavior. {ECO:0000269PubMed:17198746}.

Subcellular Localization

Disease Associations

Tissue Specificity

Expressed in various neuronal structures during embryonic development, including spinal ganglia, trigeminal nerve and ganglion, olfactory and nasopharyngeal epithelium, nuclei of the metencephalon, thalamus and medulla oblongata. Also expressed in lung, esophagus, epiglottis, ependyma, vertebral column, spinal cord and brown adipose tissue. Expression persists in the adult brain with dynamically changing patterns in cortex and cerebellum. {ECO:0000269PubMed:17198746}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	11 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000049	tRNA binding
GO:0003723	RNA binding
GO:0004809	tRNA (guanine-N2-)-methyltransferase activity
GO:0016740	transferase activity
GO:0044822	poly(A) RNA binding
GO:0046872	metal ion binding

Biological Process

GO:0008033	tRNA processing
GO:0008344	adult locomotory behavior
GO:0030488	tRNA methylation
GO:0030534	adult behavior

Cellular Component

Protein Structure and Domains

PDB ID

MGI:1916185

InterPro

IPR002905 tRNA methyltransferase, Trm1
IPR003402 tRNA transferase Trm5/Tyw2
IPR015880 Zinc finger, C2H2-like
IPR029063 S-adenosyl-L-methionine-dependent methyltransferase-like

PFAM

PF02005
PF02475

PRINTS

PIRSF

SMART

SM00355

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

A2RSY6