Version 5.4
Mus musculus Protein: Spata30
Summary
InnateDB Protein IDBP-198238.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Spata30
Protein Name RIKEN cDNA 4933424B01 gene
Synonyms 4933424B01Rik; Spata30;
Species Mus musculus
Ensembl Protein ENSMUSP00000032427
InnateDB Gene IDBG-198236 (Spata30)
Protein Structure
UniProt Annotation
Function Crucial regulator of the mitotic cell cycle and development (By similarity). At prophase, required for dynein anchoring to the nuclear envelope important for proper centrosome- nucleus coupling. At G2/M phase, may be required for proper spindle formation and execution of cytokinesis (By similarity). {ECO:0000250}.
Subcellular Localization Cytoplasm {ECO:0000269PubMed:23097494}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 11 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0007067 mitotic nuclear division
GO:0007346 regulation of mitotic cell cycle
GO:0030317 sperm motility
GO:0080154 regulation of fertilization
Cellular Component
GO:0005575 cellular_component
GO:0005634 nucleus
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID MGI:1918427
InterPro IPR019355 Cell cycle regulator Mat89Bb
PFAM PF10221
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8QZV7
PhosphoSite PhosphoSite-Q8QZV7
TrEMBL
UniProt Splice Variant
Entrez Gene 71177
UniGene
RefSeq NP_620096
MGI ID
MGI Symbol Asun
OMIM
CCDS CCDS39710
HPRD
IMGT
EMBL AC124128 BC005696 BC026851 BC027229
GenPept AAH05696 AAH26851 AAH27229

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca