InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Hspg2

Summary

InnateDB Protein

IDBP-198632.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

Hspg2

Protein Name

perlecan (heparan sulfate proteoglycan 2)

Synonyms

AI852380; Pcn; per; Plc;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000030547

InnateDB Gene

IDBG-198630 (Hspg2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 18 interaction(s) predicted by orthology.

Experimentally validated
Total	4 [view]
Protein-Protein	4 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	18 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005509	calcium ion binding
GO:0005515	protein binding

Biological Process

GO:0001958	endochondral ossification
GO:0002062	chondrocyte differentiation
GO:0007420	brain development
GO:0008104	protein localization
GO:0030198	extracellular matrix organization
GO:0048704	embryonic skeletal system morphogenesis
GO:0048738	cardiac muscle tissue development
GO:0060351	cartilage development involved in endochondral bone morphogenesis

Cellular Component

GO:0005578	proteinaceous extracellular matrix
GO:0005604	basement membrane
GO:0005605	basal lamina
GO:0031012	extracellular matrix

Protein Structure and Domains

PDB ID

MGI:96257

InterPro

IPR000034 Laminin B type IV
IPR000082 SEA domain
IPR000742 Epidermal growth factor-like domain
IPR001791 Laminin G domain
IPR001881 EGF-like calcium-binding domain
IPR002049 EGF-like, laminin
IPR002172 Low-density lipoprotein (LDL) receptor class A repeat
IPR003596 Immunoglobulin V-set, subgroup
IPR003598 Immunoglobulin subtype 2
IPR003599 Immunoglobulin subtype
IPR007110 Immunoglobulin-like domain
IPR008985 Concanavalin A-like lectin/glucanases superfamily
IPR013098 Immunoglobulin I-set
IPR013151 Immunoglobulin
IPR018031 Laminin B, subgroup

PFAM