InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Rap1gap2

Summary

InnateDB Protein

IDBP-198643.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Rap1gap2

Protein Name

RAP1 GTPase activating protein 2

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000099580

InnateDB Gene

IDBG-198641 (Rap1gap2)

Protein Structure

UniProt Annotation

Function

GTPase activator for the nuclear Ras-related regulatory protein RAP-1A (KREV-1), converting it to the putatively inactive GDP-bound state. {ECO:0000250}.

Subcellular Localization

Cytoplasm {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	0
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005096	GTPase activator activity
GO:0046582	Rap GTPase activator activity

Biological Process

GO:0010977	negative regulation of neuron projection development
GO:0032854	positive regulation of Rap GTPase activity
GO:0051056	regulation of small GTPase mediated signal transduction