InnateDB Protein
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IDBP-198645.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Rap1gap2
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Protein Name
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RAP1 GTPase activating protein 2
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Synonyms
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000040180
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InnateDB Gene
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IDBG-198641 (Rap1gap2)
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Protein Structure
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Function |
GTPase activator for the nuclear Ras-related regulatory protein RAP-1A (KREV-1), converting it to the putatively inactive GDP-bound state. {ECO:0000250}.
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Subcellular Localization |
Cytoplasm {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated |
Total |
1
[view]
|
Protein-Protein |
0
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Protein-DNA |
1
[view]
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
4 [view]
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Molecular Function |
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Biological Process |
GO:0010977
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negative regulation of neuron projection development
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GO:0032854
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positive regulation of Rap GTPase activity
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GO:0051056
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regulation of small GTPase mediated signal transduction
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Cellular Component |
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PDB ID |
MGI:3028623
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InterPro |
IPR000331
Rap GTPase activating protein domain
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PFAM |
PF02145
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q5SVL6
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PhosphoSite |
PhosphoSite-Q5SVL6
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
380711
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UniGene |
Mm.425690
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RefSeq |
NP_001015046
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MGI ID |
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MGI Symbol |
Rap1gap2
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OMIM |
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CCDS |
CCDS25032
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HPRD |
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IMGT |
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EMBL |
AK038834
AK122424
AL604065
AL627348
AL645971
BC107388
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GenPept |
AAI07389
BAC65706
BAE20542
CAI24516
CAI25407
CAI25645
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