InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Uba7

Summary

InnateDB Protein

IDBP-198746.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

Uba7

Protein Name

ubiquitin-like modifier activating enzyme 7

Synonyms

1300004C08Rik; Ube1l;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000035216

InnateDB Gene

IDBG-198744 (Uba7)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	0
Protein-DNA	2 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0005524	ATP binding
GO:0008641	small protein activating enzyme activity
GO:0019782	ISG15 activating enzyme activity

Biological Process

GO:0006464	cellular protein modification process
GO:0019941	modification-dependent protein catabolic process
GO:0032020	ISG15-protein conjugation

Cellular Component

Protein Structure and Domains

PDB ID

MGI:1349462

InterPro

IPR000011 Ubiquitin/SUMO-activating enzyme E1
IPR000127 Ubiquitin-activating enzyme repeat
IPR000594 UBA/THIF-type NAD/FAD binding fold
IPR009036 Molybdenum cofactor biosynthesis, MoeB
IPR018075 Ubiquitin-activating enzyme, E1
IPR018965 Ubiquitin-activating enzyme e1, C-terminal
IPR019572 Ubiquitin-activating enzyme

PFAM

PF02134
PF00899
PF09358
PF10585

PRINTS

PR01849

PIRSF

SMART

SM00985

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt