Version 5.4
Homo sapiens Protein: PRHOXNB
Summary
InnateDB Protein IDBP-19881.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PRHOXNB
Protein Name parahox cluster neighbor
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000333490
InnateDB Gene IDBG-19879 (PRHOXNB)
Protein Structure
UniProt Annotation
Function Catalyzes the stereoselective decarboxylation of 2-oxo- 4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) to (S)-allantoin. {ECO:0000305}.
Subcellular Localization Peroxisome {ECO:0000305}.
Disease Associations
Tissue Specificity Apparently not expressed.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0016831 carboxy-lyase activity
Biological Process
GO:0006144 purine nucleobase metabolic process
GO:0008150 biological_process
GO:0019428 allantoin biosynthetic process
GO:0019628 urate catabolic process
Cellular Component
GO:0005575 cellular_component
GO:0005777 peroxisome
Protein Structure and Domains
PDB ID
InterPro IPR017580 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase, type 1
IPR018020 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase
PFAM PF09349
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt A6NGE7
PhosphoSite PhosphoSite-A6NGE7
TrEMBL
UniProt Splice Variant
Entrez Gene 646625
UniGene Hs.705356
RefSeq NP_001099047
HUGO HGNC:17785
OMIM 615804
CCDS CCDS45020
HPRD
IMGT
EMBL AL591024
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca