Version 5.4
Mus musculus Protein: Tmem126a
Summary
InnateDB Protein IDBP-198861.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tmem126a
Protein Name transmembrane protein 126A
Synonyms 1810020E01Rik;
Species Mus musculus
Ensembl Protein ENSMUSP00000032844
InnateDB Gene IDBG-198859 (Tmem126a)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Mitochondrion inner membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity In the retina, significant levels of expression are detected in the ganglion cell layer, the optic nerve head, the outer plexiform layer, and in the outer ellipsoide length of photoreceptor inner segments. {ECO:0000269PubMed:19327736}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0021554 optic nerve development
GO:0045087 innate immune response (InnateDB)
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:1913521
InterPro IPR009801 Protein of unknown function DUF1370, TMEM126
PFAM PF07114
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9D8Y1
PhosphoSite PhosphoSite-Q9D8Y1
TrEMBL B0LAC9
UniProt Splice Variant
Entrez Gene 66271
UniGene Mm.28963
RefSeq NP_079736
MGI ID
MGI Symbol Tmem126a
OMIM
CCDS CCDS21447
HPRD
IMGT
EMBL AK007559 BC023171 EF437357
GenPept AAH23171 ABS83523 BAB25107

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca