InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Dlg2

Summary

InnateDB Protein

IDBP-198907.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

Dlg2

Protein Name

discs, large homolog 2 (Drosophila)

Synonyms

A330103J02Rik; B230218P12Rik; B330007M19Rik; Dlgh2; Gm1197; PSD93;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000073885

InnateDB Gene

IDBG-198905 (Dlg2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 15 experimentally validated interaction(s) in this database.
They are also associated with 25 interaction(s) predicted by orthology.

Experimentally validated
Total	15 [view]
Protein-Protein	14 [view]
Protein-DNA	0
Protein-RNA	1 [view]
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	25 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

GO:0007268	synaptic transmission
GO:0019233	sensory perception of pain

Cellular Component

GO:0030054	cell junction
GO:0044224	juxtaparanode region of axon
GO:0045211	postsynaptic membrane

Protein Structure and Domains

PDB ID

MGI:1344351

InterPro

IPR001452 SH3 domain
IPR001478 PDZ domain
IPR008144 Guanylate kinase-like
IPR008145 Guanylate kinase/L-type calcium channel beta subunit
IPR011511 Variant SH3 domain
IPR016313 Disks large 1
IPR019583 PDZ-associated domain of NMDA receptors
IPR019590 Membrane-associated guanylate kinase (MAGUK), PEST domain, N-terminal
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM