InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Fam82a2

Summary

InnateDB Protein

IDBP-198931.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Fam82a2

Protein Name

family with sequence similarity 82, member A2

Synonyms

1200015F23Rik; AI131757; Fam82a2; Ptpip51; RMD-3; Rmd3;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000092283

InnateDB Gene

IDBG-198929 (Fam82a2)

Protein Structure

UniProt Annotation

Function

Involved in cellular calcium homeostasis regulation (By similarity). May participate in differentiation and apoptosis of keratinocytes. Overexpression induces apoptosis (By similarity). {ECO:0000250}.

Subcellular Localization

Mitochondrion membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}. Mitochondrion outer membrane {ECO:0000250}. Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Cytoplasm, cytoskeleton, spindle {ECO:0000250}. Cytoplasm, cytoskeleton, spindle pole {ECO:0000250}. Note=In interphase localizes in the cytoplasm, and during mitosis localizes to the spindle microtubules and spindle poles. {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 23 interaction(s) predicted by orthology.

Experimentally validated
Total	4 [view]
Protein-Protein	4 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	23 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function
GO:0005515	protein binding

Biological Process

GO:0006874	cellular calcium ion homeostasis
GO:0006915	apoptotic process
GO:0030154	cell differentiation

Cellular Component

GO:0000922	spindle pole
GO:0005634	nucleus
GO:0005739	mitochondrion
GO:0005741	mitochondrial outer membrane
GO:0005874	microtubule
GO:0016021	integral component of membrane