InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Mst1

Summary

InnateDB Protein

IDBP-199177.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Mst1

Protein Name

macrophage stimulating 1 (hepatocyte growth factor-like)

Synonyms

D3F15S2h; D9H3F15S2; DNF15S2h; Hgfl;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000035211

InnateDB Gene

IDBG-199175 (Mst1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Secreted {ECO:0000305}.

Disease Associations

Tissue Specificity

Liver. Lower levels in lung, placenta and adrenal.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Experimentally validated
Total	4 [view]
Protein-Protein	4 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0004252	serine-type endopeptidase activity

Biological Process

GO:0006508	proteolysis
GO:0007283	spermatogenesis
GO:0007566	embryo implantation
GO:0030317	sperm motility

Cellular Component

GO:0005576	extracellular region
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

MGI:96080

InterPro

IPR000001 Kringle
IPR001254 Peptidase S1
IPR001314 Peptidase S1A, chymotrypsin-type
IPR003014 PAN-1 domain
IPR003609 Apple-like
IPR009003 Trypsin-like cysteine/serine peptidase domain
IPR013806 Kringle-like fold

PFAM

PF00051
PF00089
PF00024

PRINTS

PR00722

PIRSF

SMART

SM00130
SM00020
SM00473

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt