InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Psmd9

Summary

InnateDB Protein

IDBP-199347.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Psmd9

Protein Name

proteasome (prosome, macropain) 26S subunit, non-ATPase, 9

Synonyms

1500011J20Rik; 2610202L11Rik; Bridge-1; P27;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000098295

InnateDB Gene

IDBG-199345 (Psmd9)

Protein Structure

UniProt Annotation

Function

Acts as a chaperone during the assembly of the 26S proteasome, specifically of the base subcomplex of the PA700/19S regulatory complex (RC). During the base subcomplex assembly is part of an intermediate PSMD9:PSMC6:PSMC3 module, also known as modulator trimer complex; PSMD9 is released during the further base assembly process (By similarity). {ECO:0000250}.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 16 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	16 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function
GO:0003713	transcription coactivator activity
GO:0005515	protein binding
GO:0043425	bHLH transcription factor binding

Biological Process

GO:0032024	positive regulation of insulin secretion
GO:0045893	positive regulation of transcription, DNA-templated
GO:0046676	negative regulation of insulin secretion
GO:0070682	proteasome regulatory particle assembly