Version 5.4
Mus musculus Protein: Afg3l1
Summary
InnateDB Protein IDBP-199412.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Afg3l1
Protein Name AFG3(ATPase family gene 3)-like 1 (yeast)
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000095924
InnateDB Gene IDBG-199408 (Afg3l1)
Protein Structure
UniProt Annotation
Function Putative ATP-dependent protease.
Subcellular Localization Mitochondrion membrane {ECO:0000305}; Multi- pass membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0004222 metalloendopeptidase activity
GO:0005524 ATP binding
GO:0008270 zinc ion binding
GO:0017111 nucleoside-triphosphatase activity
Biological Process
GO:0006508 proteolysis
GO:0007005 mitochondrion organization
GO:0008053 mitochondrial fusion
GO:0034982 mitochondrial protein processing
GO:0042407 cristae formation
Cellular Component
GO:0005739 mitochondrion
GO:0016021 integral component of membrane
GO:0031966 mitochondrial membrane
Protein Structure and Domains
PDB ID MGI:1928277
InterPro IPR003593 AAA+ ATPase domain
IPR003959 ATPase, AAA-type, core
IPR011546 Peptidase M41, FtsH extracellular
IPR027417 P-loop containing nucleoside triphosphate hydrolase
PFAM PF00004
PF07724
PF13304
PF06480
PRINTS
PIRSF
SMART SM00382
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q920A7
PhosphoSite PhosphoSite-Q920A7
TrEMBL
UniProt Splice Variant
Entrez Gene 114896
UniGene Mm.287475
RefSeq
MGI ID
MGI Symbol Afg3l1
OMIM
CCDS
HPRD
IMGT
EMBL AF329695 AK012394 AK159647 AK167964 AK168244 BC056978
GenPept AAH56978 AAK66971 BAB28211 BAE35259 BAE39961 BAE40194

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca