Version 5.4
Mus musculus Protein: Cdc42ep3
Summary
InnateDB Protein IDBP-199462.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cdc42ep3
Protein Name CDC42 effector protein (Rho GTPase binding) 3
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000067217
InnateDB Gene IDBG-199460 (Cdc42ep3)
Protein Structure
UniProt Annotation
Function Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation in fibroblasts (By similarity). {ECO:0000250}.
Subcellular Localization Endomembrane system {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0008150 biological_process
GO:0008360 regulation of cell shape
Cellular Component
GO:0005737 cytoplasm
GO:0012505 endomembrane system
GO:0015629 actin cytoskeleton
GO:0016020 membrane
Protein Structure and Domains
PDB ID MGI:2384718
InterPro IPR000095 CRIB domain
PFAM PF00786
PRINTS
PIRSF
SMART SM00285
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9CQC5
PhosphoSite PhosphoSite-Q9CQC5
TrEMBL
UniProt Splice Variant
Entrez Gene 260409
UniGene Mm.140601
RefSeq NP_080790
MGI ID
MGI Symbol Cdc42ep3
OMIM
CCDS CCDS28984
HPRD
IMGT
EMBL AK012309 AK014281 AK019447 AK076782 AK150214 BC021409 BC034714 BC092297
GenPept AAH21409 AAH34714 AAH92297 BAB28155 BAB29241 BAB31723 BAC36479 BAE29384

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca