Version 5.4
Mus musculus Protein: Xpr1
Summary
InnateDB Protein IDBP-199784.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Xpr1
Protein Name xenotropic and polytropic retrovirus receptor 1
Synonyms Rmc-1; Rmc1; Sxv; Syg1; XR;
Species Mus musculus
Ensembl Protein ENSMUSP00000027741
InnateDB Gene IDBG-199782 (Xpr1)
Protein Structure
UniProt Annotation
Function May function in G-protein coupled signal transduction (By similarity). Potential receptor for xenotropic and polytropic murine leukemia retroviruses. {ECO:0000250, ECO:0000269PubMed:10516044, ECO:0000269PubMed:9988277}.
Subcellular Localization Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001618 virus receptor activity
GO:0004872 receptor activity
Biological Process
GO:0009615 response to virus
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:97932
InterPro IPR004331 SPX, N-terminal
IPR004342 EXS, C-terminal
PFAM PF03105
PF03124
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9Z0U0
PhosphoSite PhosphoSite-Q9Z0U0
TrEMBL E3VX18
UniProt Splice Variant
Entrez Gene 19775
UniGene Mm.408950
RefSeq NP_035403
MGI ID
MGI Symbol Xpr1
OMIM
CCDS CCDS15384
HPRD
IMGT
EMBL AF114753 AF131096 AF131098 AF198104 AK032148 AK033421 AK141660 AK147403 BC153872 HQ323662 HQ323663 HQ323664 HQ323666 HQ323667 HQ323670 HQ323671 HQ323674 HQ323675 HQ323677 HQ323678
GenPept AAD17206 AAF03482 AAF03484 AAF13256 AAI53873 ADO85653 ADO85657 ADO85658 ADO85659 ADO85661 ADO85662 ADO85665 ADO85666 ADO85669 ADO85670 ADO85672 BAC27724 BAC28279 BAE24789 BAE27891

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca