InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Cda

Summary

InnateDB Protein

IDBP-199803.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Cda

Protein Name

cytidine deaminase

Synonyms

2210401N16Rik;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000030535

InnateDB Gene

IDBG-199801 (Cda)

Protein Structure

UniProt Annotation

Function

This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. {ECO:0000250}.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0001882	nucleoside binding
GO:0003824	catalytic activity
GO:0004126	cytidine deaminase activity
GO:0008270	zinc ion binding
GO:0016787	hydrolase activity
GO:0042802	identical protein binding
GO:0042803	protein homodimerization activity

Biological Process

GO:0009972	cytidine deamination
GO:0030308	negative regulation of cell growth
GO:0045980	negative regulation of nucleotide metabolic process
GO:0051289	protein homotetramerization

Cellular Component

Protein Structure and Domains

PDB ID

MGI:1919519

InterPro

IPR002125 CMP/dCMP deaminase, zinc-binding
IPR006262 Cytidine deaminase, homotetrameric
IPR013171 Cytidine/deoxycytidylate deaminase, zinc-binding domain
IPR016193 Cytidine deaminase-like

PFAM

PF00383
PF08211

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P56389

PhosphoSite