Mus musculus Protein: Qsox1 | |||||||||||
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Summary | |||||||||||
InnateDB Protein | IDBP-199931.6 | ||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||
Gene Symbol | Qsox1 | ||||||||||
Protein Name | quiescin Q6 sulfhydryl oxidase 1 | ||||||||||
Synonyms | 1300003H02Rik; Qscn6; QSOX; SOx; | ||||||||||
Species | Mus musculus | ||||||||||
Ensembl Protein | ENSMUSP00000035658 | ||||||||||
InnateDB Gene | IDBG-199929 (Qsox1) | ||||||||||
Protein Structure | |||||||||||
UniProt Annotation | |||||||||||
Function | Catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide. May contribute to disulfide bond formation in a variety of secreted proteins (By similarity). {ECO:0000250}. | ||||||||||
Subcellular Localization | Isoform 1: Golgi apparatus membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}.Isoform 2: Secreted. Note=Found in the extracellular medium of quiescent cells but not in proliferating cells.Isoform 3: Secreted. Note=Found in the extracellular medium of quiescent cells but not in proliferating cells.Isoform 4: Secreted. Note=Found in the extracellular medium of quiescent cells but not in proliferating cells. | ||||||||||
Disease Associations | |||||||||||
Tissue Specificity | Expressed in the seminal vesicles and skin. {ECO:0000269PubMed:12354420}. | ||||||||||
Comments | |||||||||||
Interactions | |||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Protein Structure and Domains | |||||||||||
PDB ID | MGI:1330818 | ||||||||||
InterPro |
IPR012336
Thioredoxin-like fold IPR013766 Thioredoxin domain IPR017905 ERV/ALR sulfhydryl oxidase domain |
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PFAM |
PF13098
PF13192 PF13462 PF13905 PF00085 PF04777 |
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PRINTS | |||||||||||
PIRSF | |||||||||||
SMART | |||||||||||
TIGRFAMs | |||||||||||
Post-translational Modifications | |||||||||||
Modification | |||||||||||
Cross-References | |||||||||||
SwissProt | Q8BND5 | ||||||||||
PhosphoSite | PhosphoSite- | ||||||||||
TrEMBL | |||||||||||
UniProt Splice Variant | |||||||||||
Entrez Gene | 104009 | ||||||||||
UniGene | Mm.475484 | ||||||||||
RefSeq | NP_001020116 | ||||||||||
MGI ID | 3T59 | ||||||||||
MGI Symbol | Qsox1 | ||||||||||
OMIM | |||||||||||
CCDS | CCDS15386 | ||||||||||
HPRD | |||||||||||
IMGT | |||||||||||
EMBL | AB044284 AK004880 AK083938 AK149465 AK163119 AK166839 AK169877 AK169920 AK170449 BC034131 BC076590 | ||||||||||
GenPept | AAH34131 AAH76590 BAB21936 BAB23638 BAC39073 BAE28897 BAE37202 BAE39061 BAE41429 BAE41459 BAE41807 | ||||||||||