Version 5.4
Mus musculus Protein: Pla2g2f
Summary
InnateDB Protein IDBP-199960.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pla2g2f
Protein Name phospholipase A2, group IIF
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000030526
InnateDB Gene IDBG-199958 (Pla2g2f)
Protein Structure
UniProt Annotation
Function PA2 catalyzes the calcium-dependent hydrolysis of the 2- acyl groups in 3-sn-phosphoglycerides. Hydrolyzes phosphatidylglycerol with a stronger preference as compared to phosphatidylcholine. {ECO:0000269PubMed:10531313}.
Subcellular Localization Secreted.
Disease Associations
Tissue Specificity Strongly expressed in testis. {ECO:0000269PubMed:10531313}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004623 phospholipase A2 activity
GO:0005509 calcium ion binding
Biological Process
GO:0006644 phospholipid metabolic process
GO:0016042 lipid catabolic process
Cellular Component
GO:0005576 extracellular region
Protein Structure and Domains
PDB ID MGI:1349661
InterPro IPR001211 Phospholipase A2
IPR016090 Phospholipase A2 domain
PFAM PF05826
PF00068
PRINTS PR00389
PIRSF
SMART SM00085
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9QZT4
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 26971
UniGene Mm.331989
RefSeq NP_036175
MGI ID
MGI Symbol Pla2g2f
OMIM
CCDS CCDS18832
HPRD
IMGT
EMBL AF166099 AK029254 AL844178 BC125567
GenPept AAF04500 AAI25568 BAC26357 CAM21862

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca