Version 5.4
Mus musculus Protein: Asb17
Summary
InnateDB Protein IDBP-200523.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Asb17
Protein Name ankyrin repeat and SOCS box-containing 17
Synonyms 4933436O18Rik;
Species Mus musculus
Ensembl Protein ENSMUSP00000041293
InnateDB Gene IDBG-200521 (Asb17)
Protein Structure
UniProt Annotation
Function May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0008150 biological_process
GO:0016567 protein ubiquitination
GO:0035556 intracellular signal transduction
Cellular Component
GO:0005575 cellular_component
Protein Structure and Domains
PDB ID MGI:1914022
InterPro IPR001496 SOCS protein, C-terminal
IPR020683 Ankyrin repeat-containing domain
PFAM PF07525
PF11929
PF12796
PRINTS
PIRSF
SMART SM00253
SM00969
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8VHP9
PhosphoSite PhosphoSite-
TrEMBL Q3TPP7
UniProt Splice Variant
Entrez Gene 66772
UniGene Mm.116960
RefSeq NP_080034
MGI ID
MGI Symbol Asb17
OMIM
CCDS CCDS17922
HPRD
IMGT
EMBL AF425641 AK016273 AK164225 BC049572
GenPept AAH49572 AAL60518 BAE37688

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca