Version 5.4
Mus musculus Protein: Rilpl2
Summary
InnateDB Protein IDBP-200696.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Rilpl2
Protein Name Rab interacting lysosomal protein-like 2
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000031347
InnateDB Gene IDBG-200694 (Rilpl2)
Protein Structure
UniProt Annotation
Function Involved in cell shape and neuronal morphogenesis, positively regulating the establishment and maintenance of dendritic spines. Plays a role in cellular protein transport, including protein transport away from primary cilia. May function via activation of RAC1 and PAK1. {ECO:0000269PubMed:23264467}.
Subcellular Localization Cytoplasm, cytosol {ECO:0000250}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269PubMed:23264467}. Cell projection, cilium {ECO:0000269PubMed:23264467}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0042802 identical protein binding
Biological Process
GO:0003382 epithelial cell morphogenesis
GO:0006886 intracellular protein transport
Cellular Component
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0070062 extracellular vesicular exosome
GO:0072372 primary cilium
Protein Structure and Domains
PDB ID MGI:1933112
InterPro IPR021563 Rab interacting lysosomal protein
PFAM PF11461
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q99LE1
PhosphoSite PhosphoSite-Q99LE1
TrEMBL
UniProt Splice Variant
Entrez Gene 80291
UniGene
RefSeq NP_084535
MGI ID 4KP3
MGI Symbol Rilpl2
OMIM
CCDS CCDS19676
HPRD
IMGT
EMBL AK133760 AK150123 AK150252 AK171419 BC003324
GenPept AAH03324 BAE21826 BAE29324 BAE29414 BAE42441

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca