Version 5.4
Mus musculus Protein: Uqcrc1
Summary
InnateDB Protein IDBP-200730.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Uqcrc1
Protein Name ubiquinol-cytochrome c reductase core protein 1
Synonyms 1110032G10Rik;
Species Mus musculus
Ensembl Protein ENSMUSP00000026743
InnateDB Gene IDBG-200728 (Uqcrc1)
Protein Structure
UniProt Annotation
Function This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between cytochromes c and c1 (By similarity). {ECO:0000250}.
Subcellular Localization Mitochondrion inner membrane {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 19 experimentally validated interaction(s) in this database.
They are also associated with 25 interaction(s) predicted by orthology.
Experimentally validated
Total 19 [view]
Protein-Protein 19 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 25 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0005515 protein binding
GO:0032403 protein complex binding
GO:0046872 metal ion binding
Biological Process
GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c
GO:0014823 response to activity
GO:0043279 response to alkaloid
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005750 mitochondrial respiratory chain complex III
Protein Structure and Domains
PDB ID MGI:107876
InterPro IPR007863 Peptidase M16, C-terminal domain
IPR011249 Metalloenzyme, LuxS/M16 peptidase-like
IPR011765 Peptidase M16, N-terminal
PFAM PF05193
PF00675
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9CZ13
PhosphoSite PhosphoSite-Q9CZ13
TrEMBL Q8VEJ2
UniProt Splice Variant
Entrez Gene 22273
UniGene
RefSeq NP_079683
MGI ID
MGI Symbol Uqcrc1
OMIM
CCDS CCDS23540
HPRD
IMGT
EMBL AK010553 AK013128 AK151764 AK160337 BC018405 CH466560
GenPept AAH18405 BAB27022 BAB28666 BAE30670 BAE35744 EDL21324

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca