Version 5.4
Mus musculus Protein: Tyw3
Summary
InnateDB Protein IDBP-200771.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tyw3
Protein Name tRNA-yW synthesizing protein 3 homolog (S. cerevisiae)
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000057828
InnateDB Gene IDBG-200769 (Tyw3)
Protein Structure
UniProt Annotation
Function Probable S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA (By similarity). {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0008168 methyltransferase activity
Biological Process
GO:0008033 tRNA processing
GO:0008150 biological_process
GO:0032259 methylation
Cellular Component
GO:0005575 cellular_component
Protein Structure and Domains
PDB ID MGI:2445040
InterPro IPR003827 tRNA wybutosine-synthesizing protein
PFAM PF02676
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8BSA9
PhosphoSite PhosphoSite-Q8BSA9
TrEMBL
UniProt Splice Variant
Entrez Gene 209584
UniGene
RefSeq NP_766062
MGI ID
MGI Symbol Tyw3
OMIM
CCDS CCDS38680
HPRD
IMGT
EMBL AK030344 AK034820 BC086686 BC087879
GenPept AAH86686 AAH87879 BAC26913 BAC28842

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca