InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Slco2b1

Summary

InnateDB Protein

IDBP-200813.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Slco2b1

Protein Name

solute carrier organic anion transporter family, member 2b1

Synonyms

AI060904; AI852653; OATP-B; Slc21a9;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000032985

InnateDB Gene

IDBG-200811 (Slco2b1)

Protein Structure

UniProt Annotation

Function

Mediates the Na(+)-independent transport of organic anions such as taurocholate, the prostaglandins PGD2, PGE1, PGE2, leukotriene C4, thromboxane B2 and iloprost. {ECO:0000250}.

Subcellular Localization

Cell membrane; Multi-pass membrane protein.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005215	transporter activity
GO:0008514	organic anion transmembrane transporter activity
GO:0015125	bile acid transmembrane transporter activity
GO:0015347	sodium-independent organic anion transmembrane transporter activity

Biological Process

GO:0001889	liver development
GO:0006810	transport
GO:0006811	ion transport
GO:0015721	bile acid and bile salt transport
GO:0055085	transmembrane transport
GO:0071718	sodium-independent icosanoid transport

Cellular Component

GO:0005886	plasma membrane
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0016324	apical plasma membrane

Protein Structure and Domains

PDB ID

MGI:1351872

InterPro

IPR004156 Organic anion transporter polypeptide OATP
IPR011701 Major facilitator superfamily
IPR016196 Major facilitator superfamily domain, general substrate transporter

PFAM

PF03137
PF07690

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q8BXB6

PhosphoSite