Version 5.4
| Mus musculus Protein: Tnn | |||||||||
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| Summary | |||||||||
| InnateDB Protein | IDBP-201007.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Tnn | ||||||||
| Protein Name | tenascin N | ||||||||
| Synonyms | |||||||||
| Species | Mus musculus | ||||||||
| Ensembl Protein | ENSMUSP00000039452 | ||||||||
| InnateDB Gene | IDBG-201005 (Tnn) | ||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||
| Function | Isoform 2 inhibits neurite outgrowth and cell migration in hippocampal explants while isoform 1 does not have this affect. {ECO:0000269PubMed:12812753}. | ||||||||
| Subcellular Localization | Secreted, extracellular space, extracellular matrix. | ||||||||
| Disease Associations | |||||||||
| Tissue Specificity | Highest expression in kidney followed by spleen and brain. In brain, highest expression is found in hippocampus, cerebellum and olfactory bulb. {ECO:0000269PubMed:12812753}. | ||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||
| PDB ID | MGI:2665790 | ||||||||
| InterPro |
IPR000742
Epidermal growth factor-like domain IPR002181 Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain IPR003961 Fibronectin, type III IPR013111 EGF-like domain, extracellular |
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| PFAM |
PF00008
PF00147 PF00041 PF01108 PF07974 |
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| PRINTS | |||||||||
| PIRSF | |||||||||
| SMART |
SM00181
SM00186 SM00060 |
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| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | Q80Z71 | ||||||||
| PhosphoSite | PhosphoSite-Q80Z71 | ||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 329278 | ||||||||
| UniGene | Mm.90140 | ||||||||
| RefSeq | NP_808507 | ||||||||
| MGI ID | |||||||||
| MGI Symbol | Tnn | ||||||||
| OMIM | |||||||||
| CCDS | CCDS15404 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | AF455756 BC138335 BC138336 | ||||||||
| GenPept | AAI38336 AAI38337 AAO63807 | ||||||||