Version 5.4
Homo sapiens Protein: SLC25A47
Summary
InnateDB Protein IDBP-20150.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLC25A47
Protein Name solute carrier family 25, member 47
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000354886
InnateDB Gene IDBG-20146 (SLC25A47)
Protein Structure
UniProt Annotation
Function Uncoupling protein which may catalyze the physiological 'proton leak' in liver. Overexpression induces the dissipation of mitochondrial membrane potential. {ECO:0000269PubMed:15322095}.
Subcellular Localization Mitochondrion inner membrane {ECO:0000269PubMed:15322095}; Multi-pass membrane protein {ECO:0000269PubMed:15322095}.
Disease Associations
Tissue Specificity Specifically expressed in liver. {ECO:0000269PubMed:15322095}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0006810 transport
GO:0055085 transmembrane transport
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR002067 Mitochondrial carrier protein
IPR018108 Mitochondrial substrate/solute carrier
IPR023395 Mitochondrial carrier domain
PFAM PF00153
PRINTS PR00926
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6Q0C1
PhosphoSite PhosphoSite-Q6Q0C1
TrEMBL G3V374
UniProt Splice Variant
Entrez Gene 283600
UniGene Hs.108268
RefSeq NP_997000
HUGO HGNC:20115
OMIM 609911
CCDS CCDS9959
HPRD 16620
IMGT
EMBL AB073385 AK092001 AL157871 AY569438 AY570298 BC137253 BC137254 BX248260 CH471061
GenPept AAI37254 AAI37255 AAS77211 AAS80155 BAD38636 BAG52460 CAD62588 EAW81697 EAW81698

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca