Version 5.4
Mus musculus Protein: Spink8
Summary
InnateDB Protein IDBP-201542.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Spink8
Protein Name serine peptidase inhibitor, Kazal type 8
Synonyms C630041L24Rik;
Species Mus musculus
Ensembl Protein ENSMUSP00000052529
InnateDB Gene IDBG-201540 (Spink8)
Protein Structure
UniProt Annotation
Function Probable serine protease inhibitor.
Subcellular Localization Secreted {ECO:0000305}.
Disease Associations
Tissue Specificity Expressed in epydiymis, in the cauda, corpus and caput. {ECO:0000269PubMed:16930550}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004867 serine-type endopeptidase inhibitor activity
GO:0005515 protein binding
Biological Process
GO:0010951 negative regulation of endopeptidase activity
Cellular Component
GO:0005576 extracellular region
Protein Structure and Domains
PDB ID MGI:1925959
InterPro IPR002350 Kazal domain
PFAM PF00050
PF07648
PRINTS
PIRSF
SMART SM00280
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q09TK9
PhosphoSite PhosphoSite-
TrEMBL D3YYG3
UniProt Splice Variant
Entrez Gene 78709
UniGene
RefSeq NP_898959
MGI ID
MGI Symbol Spink8
OMIM
CCDS CCDS40777
HPRD
IMGT
EMBL AC163619 DQ437329
GenPept ABD93324

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca