Version 5.4
Mus musculus Protein: Suco
Summary
InnateDB Protein IDBP-201613.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Suco
Protein Name expressed sequence AI848100
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000044815
InnateDB Gene IDBG-201611 (Suco)
Protein Structure
UniProt Annotation
Function Required for bone modeling during late embryogenesis. Regulates type I collagen synthesis in osteoblasts during their postnatal maturation. {ECO:0000269PubMed:20440000}.
Subcellular Localization Rough endoplasmic reticulum membrane {ECO:0000269PubMed:20440000}; Single-pass type I membrane protein {ECO:0000269PubMed:20440000}.
Disease Associations
Tissue Specificity Present in chondrocytes, osteoblasts, osteoclasts and osteocytes (at protein level). {ECO:0000269PubMed:20440000}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0001503 ossification
GO:0007275 multicellular organismal development
GO:0032967 positive regulation of collagen biosynthetic process
GO:0045669 positive regulation of osteoblast differentiation
GO:0046850 regulation of bone remodeling
Cellular Component
GO:0005791 rough endoplasmic reticulum
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0030867 rough endoplasmic reticulum membrane
Protein Structure and Domains
PDB ID MGI:2138346
InterPro IPR008979 Galactose-binding domain-like
IPR012919 Sad1/UNC-like, C-terminal
PFAM PF07738
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8C341
PhosphoSite PhosphoSite-Q8C341
TrEMBL B2RRF3
UniProt Splice Variant
Entrez Gene 226551
UniGene Mm.410294
RefSeq NP_766233
MGI ID
MGI Symbol Suco
OMIM
CCDS CCDS48415
HPRD
IMGT
EMBL AC164414 AK029097 AK033720 AK087029 AK171856 BC138379 CH466520
GenPept AAI38380 BAC26295 BAC39786 BAE42700 BAE43286 EDL39309

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca