InnateDB Protein
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IDBP-201712.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Gtf2a1l
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Protein Name
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general transcription factor IIA, 1-like
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Synonyms
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1700011N16Rik; Alf; Gtf2a1lf;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000024970
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InnateDB Gene
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IDBG-201710 (Gtf2a1l)
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Protein Structure
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Function |
May function as a testis specific transcription factor. Binds DNA in conjunction with GTF2A2 and TBP (the TATA-binding protein) and together with GTF2A2, allows mRNA transcription.
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Subcellular Localization |
Nucleus.
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Disease Associations |
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Tissue Specificity |
Testis specific. Expressed in pachytene spermatocytes and haploid spermatids. {ECO:0000269PubMed:11159353, ECO:0000269PubMed:11889132}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
They are also associated with 18 interaction(s) predicted by orthology.
Experimentally validated |
Total |
10
[view]
|
Protein-Protein |
10
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
18 [view]
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Molecular Function |
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Biological Process |
GO:0006355
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regulation of transcription, DNA-templated
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GO:0006367
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transcription initiation from RNA polymerase II promoter
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Cellular Component |
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PDB ID |
MGI:1919078
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InterPro |
IPR004855
Transcription factor IIA, alpha/beta subunit
IPR009083
Transcription factor IIA, helical
IPR009088
Transcription factor IIA, beta-barrel
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PFAM |
PF03153
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q8R4I4
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PhosphoSite |
PhosphoSite-
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
71828
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UniGene |
Mm.61330
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RefSeq |
NP_076119
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MGI ID |
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MGI Symbol |
Gtf2a1l
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OMIM |
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CCDS |
CCDS29024
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HPRD |
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IMGT |
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EMBL |
AF250835
AF452125
AK005881
BC050756
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GenPept |
AAG50432
AAH50756
AAM12730
BAB24296
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