Mus musculus Protein: Tgm5
Summary
InnateDB Protein IDBP-201746.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tgm5
Protein Name transglutaminase 5
Synonyms 2310007C07Rik; TGMX; TGx;
Species Mus musculus
Ensembl Protein ENSMUSP00000028721
InnateDB Gene IDBG-201742 (Tgm5)
Protein Structure
UniProt Annotation
Function Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins. Contributes to the formation of the cornified cell envelope of keratinocytes (By similarity). {ECO:0000250}.
Subcellular Localization Cytoplasm {ECO:0000250}. Note=Associated with intermediate filaments. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0003810 protein-glutamine gamma-glutamyltransferase activity
GO:0046872 metal ion binding
Biological Process
GO:0018149 peptide cross-linking
Cellular Component
GO:0005575 cellular_component
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID MGI:1921426
InterPro IPR001102 Transglutaminase, N-terminal
IPR002931 Transglutaminase-like
IPR008958 Transglutaminase, C-terminal
IPR014756 Immunoglobulin E-set
PFAM PF00868
PF01841
PF00927
PRINTS
PIRSF
SMART SM00460
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9D7I9
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 74176
UniGene Mm.20187
RefSeq NP_083075
MGI ID
MGI Symbol Tgm5
OMIM
CCDS CCDS16632
HPRD
IMGT
EMBL AK009196 AK132482 AL844548
GenPept BAB26133 BAE21192 CAM19018