Version 5.4
Mus musculus Protein: Fbxo42
Summary
InnateDB Protein IDBP-201931.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Fbxo42
Protein Name F-box protein 42
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000030757
InnateDB Gene IDBG-201929 (Fbxo42)
Protein Structure
UniProt Annotation
Function Substrate-recognition component of some SCF (SKP1-CUL1- F-box protein)-type E3 ubiquitin ligase complex. Specifically recognizes p53/TP53, promoting its ubiquitination and degradation (By similarity). {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0005575 cellular_component
Protein Structure and Domains
PDB ID MGI:1924992
InterPro IPR001810 F-box domain
IPR006652 Kelch repeat type 1
IPR011498 Kelch repeat type 2
PFAM PF00646
PF12937
PF13013
PF01344
PF07646
PRINTS
PIRSF
SMART SM00256
SM00612
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6PDJ6
PhosphoSite PhosphoSite-Q6PDJ6
TrEMBL Q69ZL8
UniProt Splice Variant
Entrez Gene 213499
UniGene Mm.409304
RefSeq NP_766106
MGI ID
MGI Symbol Fbxo42
OMIM
CCDS CCDS18866
HPRD
IMGT
EMBL AK028867 AK173150 AL607087 BC003960 BC058667
GenPept AAH03960 AAH58667 BAC26160 BAD32428 CAM16991

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca