InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Cspg5

Summary

InnateDB Protein

IDBP-201945.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Cspg5

Protein Name

chondroitin sulfate proteoglycan 5

Synonyms

Caleb; Ngc;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000035058

InnateDB Gene

IDBG-201943 (Cspg5)

Protein Structure

UniProt Annotation

Function

May function as a growth and differentiation factor involved in neuritogenesis. May induce ERBB3 activation. {ECO:0000269PubMed:15848802}.

Subcellular Localization

Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Endoplasmic reticulum membrane; Single-pass type I membrane protein. Golgi apparatus membrane; Single-pass type I membrane protein. Note=Partially enriched in lipid rafts (By similarity). In neurons, localizes to synaptic junctions. Also detected in the endoplasmic reticulum and the Golgi. {ECO:0000250}.

Disease Associations

Tissue Specificity

Expressed in olfactory bulb, hippocampus, brain stem, spinal cord, cerebrum and cerebellum. Expressed by Purkinje cells in the cerebellum (at protein level). Expressed in immature and mature cerebellum (isoform 1, isoform 2 and isoform 3). {ECO:0000269PubMed:10617623, ECO:0000269PubMed:15331613, ECO:0000269PubMed:9950058}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

GO:0031103	axon regeneration
GO:0040008	regulation of growth
GO:0050804	regulation of synaptic transmission

Cellular Component

GO:0005789	endoplasmic reticulum membrane
GO:0005794	Golgi apparatus
GO:0005886	plasma membrane
GO:0016021	integral component of membrane
GO:0030660	Golgi-associated vesicle membrane