Version 5.4
Mus musculus Protein: Pipox
Summary
InnateDB Protein IDBP-201948.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pipox
Protein Name pipecolic acid oxidase
Synonyms LPIPOX; Pso;
Species Mus musculus
Ensembl Protein ENSMUSP00000017597
InnateDB Gene IDBG-201946 (Pipox)
Protein Structure
UniProt Annotation
Function Metabolizes sarcosine, L-pipecolic acid and L-proline. {ECO:0000250}.
Subcellular Localization Peroxisome {ECO:0000250}.
Disease Associations
Tissue Specificity Kidney and liver.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005102 receptor binding
GO:0008115 sarcosine oxidase activity
GO:0016491 oxidoreductase activity
GO:0050031 L-pipecolate oxidase activity
Biological Process
GO:0033514 L-lysine catabolic process to acetyl-CoA via L-pipecolate
GO:0046653 tetrahydrofolate metabolic process
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005777 peroxisome
Protein Structure and Domains
PDB ID MGI:1197006
InterPro IPR006076 FAD dependent oxidoreductase
IPR006281 Sarcosine oxidase, monomeric
PFAM PF01266
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9D826
PhosphoSite PhosphoSite-Q9D826
TrEMBL Q3UEJ8
UniProt Splice Variant
Entrez Gene 19193
UniGene Mm.8543
RefSeq NP_032978
MGI ID
MGI Symbol Pipox
OMIM
CCDS CCDS25086
HPRD
IMGT
EMBL AK008555 AK149488 BC013525 CH466596 U94700
GenPept AAC39948 AAH13525 BAB25741 BAE28913 EDL12896

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca