Mus musculus Protein: Rsg1
Summary
InnateDB Protein IDBP-201954.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Rsg1
Protein Name RIKEN cDNA 6330545A04 gene
Synonyms 6330545A04Rik; Gm723;
Species Mus musculus
Ensembl Protein ENSMUSP00000095422
InnateDB Gene IDBG-201952 (Rsg1)
Protein Structure
UniProt Annotation
Function Potential effector of the planar cell polarity signaling pathway. Plays a role in targeted membrane trafficking most probably at the level of vesicle fusion with membranes. Involved in cilium biogenesis by regulating the transport of cargo proteins to the basal body and to the apical tips of cilia. More generally involved in exocytosis in secretory cells (By similarity). {ECO:0000250}.
Subcellular Localization Cytoplasm, cytoskeleton, cilium basal body {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005525 GTP binding
Biological Process
GO:0006887 exocytosis
GO:0007264 small GTPase mediated signal transduction
GO:0015031 protein transport
GO:0017157 regulation of exocytosis
GO:0031338 regulation of vesicle fusion
GO:0034613 cellular protein localization
GO:0042384 cilium assembly
Cellular Component
GO:0005575 cellular_component
GO:0005622 intracellular
GO:0005737 cytoplasm
GO:0036064 ciliary basal body
Protein Structure and Domains
PDB ID MGI:1923416
InterPro IPR001806 Small GTPase superfamily
IPR013684 Mitochondrial Rho-like
IPR027417 P-loop containing nucleoside triphosphate hydrolase
PFAM PF00071
PF08477
PRINTS PR00449
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt A2A825
PhosphoSite PhosphoSite-A2A825
TrEMBL B2RWG6
UniProt Splice Variant
Entrez Gene 76166
UniGene
RefSeq NP_001074643
MGI ID
MGI Symbol Rsg1
OMIM
CCDS CCDS38937
HPRD
IMGT
EMBL AL607087 BC147765 BC147767 CH466615
GenPept AAI47766 AAI47768 CAM16992 EDL13352