Version 5.4
| Mus musculus Protein: Arhgef19 | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Summary | |||||||||
| InnateDB Protein | IDBP-201966.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Arhgef19 | ||||||||
| Protein Name | Rho guanine nucleotide exchange factor (GEF) 19 | ||||||||
| Synonyms | |||||||||
| Species | Mus musculus | ||||||||
| Ensembl Protein | ENSMUSP00000006618 | ||||||||
| InnateDB Gene | IDBG-201964 (Arhgef19) | ||||||||
| Protein Structure |
|
||||||||
| UniProt Annotation | |||||||||
| Function | Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase. {ECO:0000269PubMed:15485661}. | ||||||||
| Subcellular Localization | |||||||||
| Disease Associations | |||||||||
| Tissue Specificity | Highly expressed in intestine, and at lower levels in liver, heart and kidney. {ECO:0000269PubMed:15485661}. | ||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
|
||||||||
| Gene Ontology | |||||||||
Molecular Function |
|
||||||||
| Biological Process |
|
||||||||
| Cellular Component |
|
||||||||
| Protein Structure and Domains | |||||||||
| PDB ID | MGI:1925912 | ||||||||
| InterPro |
IPR000219
Dbl homology (DH) domain IPR001452 SH3 domain IPR001849 Pleckstrin homology domain IPR011511 Variant SH3 domain |
||||||||
| PFAM |
PF00621
PF00018 PF14604 PF00169 PF07653 |
||||||||
| PRINTS |
PR00452
|
||||||||
| PIRSF | |||||||||
| SMART |
SM00325
SM00326 SM00233 |
||||||||
| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | Q8BWA8 | ||||||||
| PhosphoSite | PhosphoSite-Q8BWA8 | ||||||||
| TrEMBL | A2A829 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 213649 | ||||||||
| UniGene | Mm.134460 | ||||||||
| RefSeq | NP_766108 | ||||||||
| MGI ID | |||||||||
| MGI Symbol | Arhgef19 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS18868 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | AK053075 AL607087 BC060376 | ||||||||
| GenPept | AAH60376 BAC35256 CAM16998 | ||||||||