Version 5.4
Mus musculus Protein: Elp6
Summary
InnateDB Protein IDBP-201969.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Elp6
Protein Name RIKEN cDNA 2610002I17
Synonyms 2610001P13Rik; 2610002I17Rik; AV159994; Tmem103;
Species Mus musculus
Ensembl Protein ENSMUSP00000069017
InnateDB Gene IDBG-201967 (Elp6)
Protein Structure
UniProt Annotation
Function Acts as subunit of the RNA polymerase II elongator complex, which is a histone acetyltransferase component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4. Involved in cell migration. {ECO:0000269PubMed:22854966}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0030335 positive regulation of cell migration
Cellular Component
GO:0033588 Elongator holoenzyme complex
Protein Structure and Domains
PDB ID MGI:1919349
InterPro IPR018627 Uncharacterised protein family UPF0405
PFAM PF09807
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8BK75
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 72341
UniGene Mm.374250
RefSeq NP_001074850
MGI ID
MGI Symbol Elp6
OMIM
CCDS CCDS52937
HPRD
IMGT
EMBL AK011270 AK075986 BC048732
GenPept AAH48732 BAB27508 BAC36098

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca