Version 5.4
Mus musculus Protein: Art2b
Summary
InnateDB Protein IDBP-202136.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Art2b
Protein Name ADP-ribosyltransferase 2b
Synonyms Art; ART2.2; ARTC2; Ly92b; Rt-6; Rt6; Rt6-2;
Species Mus musculus
Ensembl Protein ENSMUSP00000065658
InnateDB Gene IDBG-202134 (Art2b)
Protein Structure
UniProt Annotation
Function Has both NAD(+) glycohydrolase and ADP- ribosyltransferase activity. {ECO:0000269PubMed:17928361, ECO:0000269PubMed:9300695}.
Subcellular Localization Cell membrane {ECO:0000250}; Lipid-anchor, GPI-anchor {ECO:0000250}.
Disease Associations
Tissue Specificity Expressed in spleen, intestine and thymus. {ECO:0000269PubMed:9300695}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity
GO:0016798 hydrolase activity, acting on glycosyl bonds
Biological Process
GO:0006471 protein ADP-ribosylation
GO:0018120 peptidyl-arginine ADP-ribosylation
GO:0019677 NAD catabolic process
Cellular Component
GO:0016020 membrane
GO:0019897 extrinsic component of plasma membrane
GO:0031362 anchored component of external side of plasma membrane
Protein Structure and Domains
PDB ID MGI:107545
InterPro IPR000768 NAD:arginine ADP-ribosyltransferase, ART
PFAM PF01129
PRINTS PR00970
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O35975
PhosphoSite PhosphoSite-O35975
TrEMBL
UniProt Splice Variant
Entrez Gene 11872
UniGene Mm.57008
RefSeq NP_064299
MGI ID
MGI Symbol Art2b
OMIM
CCDS CCDS21512
HPRD
IMGT
EMBL AC129609 AF016463 AF016465 X87612
GenPept AAB71683 AAB71684 CAA60948

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca