InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Strc

Summary

InnateDB Protein

IDBP-202183.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Strc

Protein Name

stereocilin

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000039378

InnateDB Gene

IDBG-202181 (Strc)

Protein Structure

UniProt Annotation

Function

Essential to the formation of horizontal top connectors between outer hair cell stereocilia. {ECO:0000269PubMed:21165971}.

Subcellular Localization

Cell surface. Cell projection, kinocilium. Cell projection, stereocilium.

Disease Associations

Tissue Specificity

Strongly expressed in the inner ear, detected in the testis, and barely detected in the eye. Detected in the six sensory areas of the inner ear by immunofluorescence. Expressed only in the sensory hair cells and associated with the stereocilia, the stiff microvilli forming the structure for mechanoreception of sound stimulation. {ECO:0000269PubMed:11687802, ECO:0000269PubMed:21165971}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function
GO:0004871	signal transducer activity

Biological Process

GO:0000160	phosphorelay signal transduction system
GO:0007605	sensory perception of sound
GO:0050910	detection of mechanical stimulus involved in sensory perception of sound
GO:0060088	auditory receptor cell stereocilium organization