InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Scyl3

Summary

InnateDB Protein

IDBP-202192.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Scyl3

Protein Name

SCY1-like 3 (S. cerevisiae)

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000027876

InnateDB Gene

IDBG-202190 (Scyl3)

Protein Structure

UniProt Annotation

Function

May play a role in regulating cell adhesion/migration complexes in migrating cells.

Subcellular Localization

Cytoplasm {ECO:0000250}. Golgi apparatus {ECO:0000250}. Cell projection, lamellipodium {ECO:0000250}. Note=Colocalized with EZR/VIL2, actin and CD44 in lamellipodia. {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004672	protein kinase activity
GO:0005488	binding
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0016772	transferase activity, transferring phosphorus-containing groups

Biological Process

GO:0006468	protein phosphorylation
GO:0008150	biological_process

Cellular Component

GO:0005737	cytoplasm
GO:0005794	Golgi apparatus
GO:0030027	lamellipodium

Protein Structure and Domains

PDB ID

MGI:1921385

InterPro

IPR000719 Protein kinase domain
IPR002290 Serine/threonine- /dual specificity protein kinase, catalytic domain
IPR011009 Protein kinase-like domain
IPR016024 Armadillo-type fold

PFAM

PF00069

PRINTS

PIRSF

SMART

SM00220

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9DBQ7