Version 5.4
Mus musculus Protein: Kctd7
Summary
InnateDB Protein IDBP-202242.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Kctd7
Protein Name potassium channel tetramerisation domain containing 7
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000044568
InnateDB Gene IDBG-202240 (Kctd7)
Protein Structure
UniProt Annotation
Function May be involved in the control of excitability of cortical neurons. {ECO:0000269PubMed:21710140}.
Subcellular Localization Cell membrane {ECO:0000250}. Cytoplasm, cytosol {ECO:0000250}.
Disease Associations
Tissue Specificity High expression in brain, particularly in post-mitotic neurons. Expressed in the mitral cells of the olfactory bulbs, the hippocampus, the deep layers of the cerebral cortex and Purkinje cells of the cerebellum. Not detected in astrocytes or microglial cells. Also expressed in heart, liver, spleen and kidney. {ECO:0000269PubMed:21710140, ECO:0000269PubMed:22693283, ECO:0000269PubMed:22748208}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0008150 biological_process
GO:0051260 protein homooligomerization
Cellular Component
GO:0005575 cellular_component
GO:0005829 cytosol
GO:0005886 plasma membrane
Protein Structure and Domains
PDB ID MGI:2442265
InterPro IPR000210 BTB/POZ-like
IPR003131 Potassium channel tetramerisation-type BTB domain
IPR011333 BTB/POZ fold
PFAM PF02214
PRINTS
PIRSF
SMART SM00225
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8BJK1
PhosphoSite PhosphoSite-Q8BJK1
TrEMBL
UniProt Splice Variant
Entrez Gene 212919
UniGene Mm.55812
RefSeq NP_766097
MGI ID
MGI Symbol Kctd7
OMIM
CCDS CCDS19707
HPRD
IMGT
EMBL AK029942 AK083583 AK140606 BC051544 BC139070 BC141201 CH466529
GenPept AAH51544 AAI39071 AAI41202 BAC26691 BAC38959 BAE24427 EDL19476

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca