InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Tbx19

Summary

InnateDB Protein

IDBP-202558.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Tbx19

Protein Name

T-box 19

Synonyms

AU019250; D1Ertd754e; Tpit;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000027859

InnateDB Gene

IDBG-202556 (Tbx19)

Protein Structure

UniProt Annotation

Function

Transcriptional regulator involved in developmental processes. Can activate POMC gene expression and repress the alpha glycoprotein subunit and thyroid-stimulating hormone beta promoters. {ECO:0000269PubMed:11290323}.

Subcellular Localization

Nucleus {ECO:0000255PROSITE- ProRule:PRU00201}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0001158	enhancer sequence-specific DNA binding
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0005515	protein binding

Biological Process

GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0021983	pituitary gland development
GO:0042127	regulation of cell proliferation
GO:0045165	cell fate commitment
GO:0045595	regulation of cell differentiation
GO:0045944	positive regulation of transcription from RNA polymerase II promoter