InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Patl2

Summary

InnateDB Protein

IDBP-202701.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Patl2

Protein Name

protein associated with topoisomerase II homolog 2 (yeast)

Synonyms

4930424G05Rik; Pat1a;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000028665

InnateDB Gene

IDBG-202699 (Patl2)

Protein Structure

UniProt Annotation

Function

RNA-binding protein that acts as a translational repressor. {ECO:0000250}.

Subcellular Localization

Cytoplasm {ECO:0000269PubMed:20826699}. Nucleus {ECO:0000269PubMed:20826699}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0002151	G-quadruplex RNA binding
GO:0003723	RNA binding
GO:0005515	protein binding
GO:0008266	poly(U) RNA binding
GO:0030371	translation repressor activity
GO:0034046	poly(G) binding

Biological Process

GO:0010607	negative regulation of cytoplasmic mRNA processing body assembly
GO:0017148	negative regulation of translation

Cellular Component

GO:0000932	cytoplasmic mRNA processing body
GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0030529	ribonucleoprotein complex

Protein Structure and Domains

PDB ID

MGI:1914828

InterPro

IPR019167 Topoisomerase II-associated protein PAT1

PFAM

PF09770

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

A2ARM1

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

67578

UniGene

Mm.150462

RefSeq

NP_080527

MGI ID

MGI Symbol

Patl2

OMIM

CCDS

CCDS16653

HPRD

IMGT

EMBL

AK015195 AL845457 BC145646

GenPept

AAI45647 BAB29742 CAM21782