Mus musculus Protein: Stac
Summary
InnateDB Protein IDBP-202886.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Stac
Protein Name src homology three (SH3) and cysteine rich domain
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000035083
InnateDB Gene IDBG-202882 (Stac)
Protein Structure
UniProt Annotation
Function Probably involved in a neuron-specific signal transduction.
Subcellular Localization Cytoplasm.
Disease Associations
Tissue Specificity Expressed predominantly in brain and neurons, more specifically in hippocampus, cerebellum and inferior olive. Weak expression is found in heart, liver, lung and kidney. Found as well in some cell lines.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
GO:0046872 metal ion binding
Biological Process
GO:0034605 cellular response to heat
GO:0035556 intracellular signal transduction
Cellular Component
GO:0005575 cellular_component
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID MGI:1201400
InterPro IPR001452 SH3 domain
IPR002219 Protein kinase C-like, phorbol ester/diacylglycerol binding
IPR011511 Variant SH3 domain
IPR013315 Spectrin alpha chain, SH3 domain
PFAM PF00018
PF14604
PF00130
PF07653
PRINTS PR00452
PR01887
PIRSF
SMART SM00326
SM00109
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P97306
PhosphoSite PhosphoSite-P97306
TrEMBL Q3UPL9
UniProt Splice Variant
Entrez Gene 20840
UniGene Mm.1414
RefSeq NP_058549
MGI ID
MGI Symbol Stac
OMIM
CCDS CCDS23586
HPRD
IMGT
EMBL AK143440 BC107325 BC107326 CH466621 D86639
GenPept AAI07326 AAI07327 BAA13151 BAE25376 EDL08969