Version 5.4
| Homo sapiens Protein: SPINK2 | |||||||||
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| Summary | |||||||||
| InnateDB Protein | IDBP-20303.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | SPINK2 | ||||||||
| Protein Name | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) | ||||||||
| Synonyms | HUSI-II; | ||||||||
| Species | Homo sapiens | ||||||||
| Ensembl Protein | ENSP00000248701 | ||||||||
| InnateDB Gene | IDBG-20299 (SPINK2) | ||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||
| Function | Strong inhibitor of acrosin in male and/or female genital tract. Also inhibits trypsin. {ECO:0000269PubMed:19422058}. | ||||||||
| Subcellular Localization | Secreted. | ||||||||
| Disease Associations | |||||||||
| Tissue Specificity | Expressed in epididymis (at protein level). {ECO:0000269PubMed:20736409}. | ||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||
| PDB ID | |||||||||
| InterPro |
IPR002350
Kazal domain |
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| PFAM |
PF00050
PF07648 |
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| PRINTS | |||||||||
| PIRSF | |||||||||
| SMART |
SM00280
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| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | P20155 | ||||||||
| PhosphoSite | PhosphoSite-P20155 | ||||||||
| TrEMBL | A0A024RD95 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 6691 | ||||||||
| UniGene | Hs.98243 | ||||||||
| RefSeq | NP_066937 | ||||||||
| HUGO | HGNC:11245 | ||||||||
| OMIM | 605753 | ||||||||
| CCDS | CCDS3508 | ||||||||
| HPRD | 10422 | ||||||||
| IMGT | |||||||||
| EMBL | AK312222 BC022514 CH471057 CR542135 GU727622 M84967 M91438 X57655 | ||||||||
| GenPept | AAB59431 AAH22514 ADU87624 BAG35155 CAB37834 CAG46932 EAX05513 EAX05514 | ||||||||