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InnateDB Protein
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IDBP-203060.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Ift20
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Protein Name
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intraflagellar transport 20 homolog (Chlamydomonas)
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Synonyms
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0610009H04Rik; AU015496;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000051699
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InnateDB Gene
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IDBG-203058 (Ift20)
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Protein Structure
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| Function |
Part of intraflagellar transport (IFT) particles involved in ciliary process assembly. May play a role in the trafficking of ciliary membrane proteins from the Golgi complex to the cilium. Also involved in autophagy since it is required for trafficking of ATG16L and the expansion of the autophagic compartment. {ECO:0000269PubMed:16775004, ECO:0000269PubMed:24089209}.
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| Subcellular Localization |
Golgi apparatus, cis-Golgi network. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, cilium basal body. Note=Present at the centrosomes during the cell cycle and associated with the proximal portion of the mother centriole and the lateral aspect of the daughter centriole. Associated with basal body at the base of primary cilia.
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| Disease Associations |
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| Tissue Specificity |
Expressed in testis, kidney and retina. {ECO:0000269PubMed:11916979, ECO:0000269PubMed:12821668}.
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| Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.
| Experimentally validated |
| Total |
5
[view]
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| Protein-Protein |
5
[view]
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| Protein-DNA |
0
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| Protein-RNA |
0
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| DNA-DNA |
0
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| RNA-RNA |
0
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| DNA-RNA |
0
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| Predicted by orthology |
| Total |
11 [view]
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| PDB ID |
MGI:1915585
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| InterPro |
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| PFAM |
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| PRINTS |
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| PIRSF |
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| SMART |
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| TIGRFAMs |
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| Modification |
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| SwissProt |
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| PhosphoSite |
PhosphoSite-
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| TrEMBL |
Z4YJL9
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| UniProt Splice Variant |
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| Entrez Gene |
55978
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| UniGene |
Mm.437824
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| RefSeq |
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| MGI ID |
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| MGI Symbol |
Ift20
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| OMIM |
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| CCDS |
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| HPRD |
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| IMGT |
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| EMBL |
AL591177
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| GenPept |
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Version 5.4