InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Nsun5

Summary

InnateDB Protein

IDBP-203782.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Nsun5

Protein Name

NOL1/NOP2/Sun domain family, member 5

Synonyms

9830109N13Rik; AI326939; Nol1r; Wbscr20; Wbscr20a;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000000940

InnateDB Gene

IDBG-203780 (Nsun5)

Protein Structure

UniProt Annotation

Function

S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the C(5) position of a cytosine in 28S rRNA. {ECO:0000250}.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003723	RNA binding
GO:0008168	methyltransferase activity
GO:0044822	poly(A) RNA binding

Biological Process

GO:0008150	biological_process
GO:0032259	methylation

Cellular Component

GO:0005634	nucleus
GO:0005730	nucleolus

Protein Structure and Domains

PDB ID

MGI:2140844

InterPro

IPR001678 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p
IPR023267 RNA (C5-cytosine) methyltransferase
IPR029063 S-adenosyl-L-methionine-dependent methyltransferase-like

PFAM

PF01189

PRINTS

PR02008

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q8K4F6