Version 5.4
Mus musculus Protein: Rhbdd2
Summary
InnateDB Protein IDBP-203990.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Rhbdd2
Protein Name rhomboid domain containing 2
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000049060
InnateDB Gene IDBG-203988 (Rhbdd2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Golgi apparatus, cis-Golgi network membrane {ECO:0000269PubMed:23386608}; Multi-pass membrane protein {ECO:0000269PubMed:23386608}.
Disease Associations
Tissue Specificity Widely expressed, including in retina and brain (at protein level), as well as in kidney, testis and ovary. Expressed in all layers of the retina, including inner segments of photoreceptor cells and ganglion cells (at protein level). {ECO:0000269PubMed:23386608}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0004252 serine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis
GO:0008150 biological_process
Cellular Component
GO:0000139 Golgi membrane
GO:0005634 nucleus
GO:0005794 Golgi apparatus
GO:0016021 integral component of membrane
GO:0048471 perinuclear region of cytoplasm
Protein Structure and Domains
PDB ID MGI:1915612
InterPro IPR022764 Peptidase S54, rhomboid domain
PFAM PF01694
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8VEK2
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 215160
UniGene Mm.464311
RefSeq NP_666114
MGI ID
MGI Symbol Rhbdd2
OMIM
CCDS CCDS19743
HPRD
IMGT
EMBL AK041845 AK161545 AK165926 BC018360 BC098493
GenPept AAH18360 AAH98493 BAC31081 BAE36454 BAE38463

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca