Version 5.4
Mus musculus Protein: Rhbdl3
Summary
InnateDB Protein IDBP-204150.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Rhbdl3
Protein Name rhomboid, veinlet-like 3 (Drosophila)
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000017836
InnateDB Gene IDBG-204146 (Rhbdl3)
Protein Structure
UniProt Annotation
Function May be involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors. {ECO:0000250}.
Subcellular Localization Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004252 serine-type endopeptidase activity
GO:0005509 calcium ion binding
Biological Process
GO:0006508 proteolysis
GO:0008150 biological_process
Cellular Component
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:2179276
InterPro IPR002048 EF-hand domain
IPR017213 Peptidase S54, rhomboid, metazoan
IPR022764 Peptidase S54, rhomboid domain
PFAM PF00036
PF13202
PF13405
PF01694
PRINTS
PIRSF PIRSF037470
SMART SM00054
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P58873
PhosphoSite PhosphoSite-P58873
TrEMBL
UniProt Splice Variant
Entrez Gene 246104
UniGene Mm.194148
RefSeq NP_631974
MGI ID
MGI Symbol Rhbdl3
OMIM
CCDS CCDS25131
HPRD
IMGT
EMBL AJ313479 BC054784 BC056969
GenPept AAH54784 AAH56969 CAC86144

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca